Rachel H. Jacobs, Ph.D.
PROJECT TITLE Protecting Adolescents from Recurrent Depression by Targeting Rumination PROJECT SUMMARY Currently, approximately 50% of individuals who experience depression during their adolescence experience depression again. No current treatments protect against the lifelong consequences of depression in one’s youth. This project seeks to therapeutically modulate the brain circuitry underlying rumination, a passive and maladaptive thought […]
Katie L. Burkhouse, Ph.D.
PROJECT TITLE Targeting Biomarkers of Risk among Offspring of Depressed Parents through Family Cognitive Behavioral Preventive Intervention PROJECT SUMMARY Offspring of depressed parents, a population at extremely high risk for developing major depressive disorder (MDD), are characterized by deficits in reward and social-emotional processing at the neural level. Specifically, the reward positivity (RewP), an event-related […]